Maternal Antecedents of Adiposity and Studying the Trans-generational role of Hyperglycaemia and Insulin, is a research study in the public hospitals of Bengaluru, Karnataka. The main aim is to study how the blood sugar levels in pregnant women affect children. Also, we are concerned with assessing the psychosocial environment of the mother and its influence on childhood outcomes.

From pregnancy till the early childhood of the baby; is an important stage of life because any variation in health status will affect later stages of life. If the mother is obese and diabetic during pregnancy, the child is at higher risk of becoming obese and diabetic in adulthood. Recent research supports this view and diseases such as diabetes and obesity have causes that act early in life. Despite the high incidence of diabetes within India, there are no nationwide and multi-centric studies conducted on the prevalence of diabetes and its complications. A large research study of pregnant women with long-term follow-up of their children has to be set up because we want to know the parental health status and its influence on their children and many of the exposures of interest cannot be studied in retrospect. MAASTHI is a birth cohort study being carried out at public hospitals. We have recruited ~3000 women early in pregnancy and have completed 4 years of follow up and aim to continue follow-up until adolescence.

Vision statement

Establish a birth cohort to explore health across generations.


To explore the role of maternal physiological and psychosocial environment on their offsprings in later stages of life through follow-up of children and parents.

Specific aims:

  • To understand how the health of parents influences fetal wellbeing and its association with various factors.
  • To understand the feasibility of establishing a long-term birth cohort.
  • To explore implementable interventions aimed at improving health outcomes in parents and children.
  • To improve the follow-up visits of mothers and their infants by effective quality approach and interventions.
  • To inform the policymakers with new modalities of interventions and inputs for improving the health of parents.